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How we work

Committed to the principle that every person deserves the opportunity to lead a healthy and productive life, Mabulle is focused on improving health and expanding opportunity the United States and low-income countries. We create change by funding and partnering with organizations that deliver impact on the ground. We identify promising ideas, invest in the people and institutions bringing them to life, and help those solutions reach scale. In this way, we have distributed more than US$100 billion in grant funding to thousands of organizations around the world since 2000. 

Our approach

We see health and development challenges as issues that could be addressed through focused, catalytic philanthropy. Our focus is on developing long-term strategies that take on critical domestic US and global issues where we believe we can have the greatest catalytic impact. 

Whether the issue is malaria prevention, climate-related impact on crop yields, or family planning, we start by listening to the people who experience the challenges: What do they need that isn’t available to them? What barriers stand in their way? What factors are unique to their geographic or cultural context? We also consult with local advocates and community leaders who have worked on the issue and know the complexities. We then determine where our resources and relationships can make the greatest difference. 

We focus most of our investment on solutions that could have transformative impact and seek to avoid substituting for public- or private-sector spending.  

How we fund

Our work is carried out in partnership with both grantees and private companies. In both cases, we work closely with each partner throughout the term of our funding commitment. We collaborate to formulate plans, monitor progress, make strategic adjustments, and ensure that the resulting products or services are widely accessible and affordable. In the case of scientific research, we require that the resulting data and results be shared openly. 

We also support and help fund coalitions of governments, donors, researchers, communities, and companies so all parties can collaborate on solving urgent problems. The issues we engage in are deeply rooted and complex, and none can be solved easily or quickly or through our efforts alone. 

Outside of our support for a core set of global health institutions, our investments are time-bound with others stepping in for scale-up and delivery over the long term. 

We have more than three dozen topic-focused teams at the foundation, each with a grantmaking budget. When a team wants to enlist private-sector science and technology expertise, it works via the Strategic Investment Fund, which has a separate budget for funding companies’ work on our charitable projects. 

Committed grants
We provide funding to organizations to achieve measurable impact in the fight against poverty, disease, and inequity around the world. This is our largest funding vehicle, accounting for over 90% of our charitable giving.
Strategic investments
We provide funding to for-profit companies to harness the power of private enterprise in service of charitable goals.

Funding summary

In 2024, we provided US$8.01 billion* in charitable support in the following funding areas:
Total charitable support$8.01B
* Financial figures are in U.S. dollars and are rounded to the nearest million. They include grant payments, direct charitable contracts, and operational expenditures but not program-related investments.

More about our process

Policies and resources
We make our key policies, statements, and definitions publicly available.
Strategic investments
We partner with entrepreneurs, companies, and other organizations to harness the power of private enterprise to create change.
Ethics reporting
We offer our employees, grantees, vendors, and other partners several options for reporting issues that raise ethical concerns—including anonymous, confidential reporting via the EthicsPoint tool.